Blood-Pressure
Impact of Ultra-Early Perioperative Antihypertensive Therapy in Acute Intracerebral Hemorrhage — INTERACT3 Secondary Analysis
In INTERACT3 surgical-evacuation patients, achieving systolic BP <140 mm Hg within 2 hours was associated with lower death or disability, better mRS shift, fewer serious adverse events, and no increase in mortality.
Personalized Blood Pressure Targeting After Endovascular Therapy for Acute Ischemic Stroke — A Randomized Clinical Trial
In the HOPE randomized trial, reperfusion-guided systolic blood-pressure targets after thrombectomy increased 90-day functional independence from 47.1% to 60.0% without increasing symptomatic intracranial hemorrhage or mortality.