Head-of-Bed-Positioning

• Deep-Dive: ZODIAC — Laying LVO Patients Flat Before Thrombectomy Cuts Pre-Procedure Deterioration 26-Fold

  August 12, 2026

  ZODIAC phase III RCT (n=92, stopped early for efficacy): 0° vs 30° head-of-bed positioning before thrombectomy — END HR 34.40 (95% CI 4.65–254.37), P<0.001; exploratory mortality P=0.03.