Neuroprotection
Edaravone dexborneol versus placebo on functional outcomes in patients with acute ischaemic stroke undergoing endovascular thrombectomy (TASTE-2): randomised controlled trial
In selected Chinese patients with anterior-circulation large-vessel occlusion treated by thrombectomy, edaravone dexborneol produced a borderline increase in 90-day functional independence without a detected increase in serious adverse events.
Multicenter Translational Trial of Remote Ischemic Conditioning in Acute Ischemic Stroke (TRICS BASIC)
Multicenter preclinical RCT of remote ischemic conditioning in rodent stroke models: 55% vs 36% good functional outcome at 48 hours.