Target-Trial-Emulation

• Defining the Therapeutic Ceiling of Endovascular Thrombectomy in Large-Core Stroke — Beyond the Limits of ASPECTS

  September 19, 2026

  Quantitative infarct volumetry — not NCCT-ASPECTS — sets the true ceiling for endovascular thrombectomy in large-core stroke: benefit holds up to a DWI core of roughly 110 mL, then collapses.